The CryoCooler is a valuable tool that helps to preserve the integrity of frozen vials of cultured cells and tissue specimens during routine handling.  The CryoCooler well contains a pillow that adsorbs liquid nitrogen.  Once charged, the pillow slowly releases liquid nitrogen vapor which can keep samples in the CryoCooler's well at temperatures below -130°C for up to five hours. The CryoCooler is very useful for preparing stored tissue for RNA isolation or for the sorting of frozen vials.