1.4 mm Zirconium Beads in a disruption tube
Our 1.4 mm Zirconium Beads (Zirconium Silicate) are suitable for homogenizing small animal (e.g., mouse) tissue samples and biomass and comparable to Lysing Matrix D.
Zirconium Beads are denser than silica beads, less expensive than stainless steel grinding balls, and inert in most solutions. They are washed with acidified water to remove contaminants typically found in untreated beads (e.g., dust, microbes, hair), and further baked to remove any organic impurities.
Pre-Filled Tubes are a convenient solution for labs seeking time savings by no longer requiring researchers to weigh, fill and QC individual tubes. They are available in 2 mL skirted (i.e., self-standing) or unskirted polypropylene tubes to ensure compatibility with most tube homogenizers. Clear screw caps with O-rings included.
Citations
van Putten, M.; Tanganyika-de Winter, C.; Bosgra, S.; Aartsma-Rus, A. Nonclinical Exon Skipping Studies with 2′-O-Methyl Phosphorothioate Antisense Oligonucleotides in Mdx and Mdx-Utrn−/− Mice Inspired by Clinical Trial Results. Nucleic Acid Therapeutics 2019, 29 (2), 92–103. https://doi.org/10.1089/nat.2018.0759.
Kemaladewi, D. U.; Benjamin, J. S.; Hyatt, E.; Ivakine, E. A.; Cohn, R. D. Increased Polyamines as Protective Disease Modifiers in Congenital Muscular Dystrophy. Hum Mol Genet 2018, 27 (11), 1905–1912. https://doi.org/10.1093/hmg/ddy097.
Saunte, D.; Hare, R.; Jorgensen, K.; Jorgensen, R.; Deleuran, M.; Zachariae, C.; Thomsen, S.; Bjornskov-Halkier, L.; Kofoed, K.; Arendrup, M. Emerging Terbinafine Resistance in Trichophyton: Clinical Characteristics, Squalene Epoxidase Gene Mutations, and a Reliable EUCAST Method for Detection. - Abstract - Europe PMC https://europepmc.org/article/med/31383665#free-full-text (accessed Mar 28, 2020).
Johnson, C. T.; Wroe, J. A.; Agarwal, R.; Martin, K. E.; Guldberg, R. E.; Donlan, R. M.; Westblade, L. F.; García, A. J. Hydrogel Delivery of Lysostaphin Eliminates Orthopedic Implant Infection by Staphylococcus Aureus and Supports Fracture Healing. PNAS 2018, 115 (22), E4960–E4969. https://doi.org/10.1073/pnas.1801013115.
Kogelman, B.; Putker, K.; Hulsker, M.; Tanganyika-de Winter, C.; van der Weerd, L.; Aartsma-Rus, A.; van Putten, M. Voluntary Exercise Improves Muscle Function and Does Not Exacerbate Muscle and Heart Pathology in Aged Duchenne Muscular Dystrophy Mice. Journal of Molecular and Cellular Cardiology 2018, 125, 29–38. https://doi.org/10.1016/j.yjmcc.2018.10.008.
Koban, R.; Neumann, M.; Daugs, A.; Bloch, O.; Nitsche, A.; Langhammer, S.; Ellerbrok, H. A Novel Three-Dimensional Cell Culture Method Enhances Antiviral Drug Screening in Primary Human Cells. Antiviral Research 2018, 150, 20–29. https://doi.org/10.1016/j.antiviral.2017.12.005.
