Convenient, ready-to-use, and designed for labs using solvents incompatible with polycarbonate (e.g., Trizol and TRI Reagent), our 24 Well Polyethylene Vial Sets with Lined Caps are a practiced alternative. Resistant to many solvents that melt polycarbonate, cost-effective Polyethylene Vial Sets are suitable for high throughput homogenization of most small seeds and animal tissue. Polyethylene-Lined Polypropylene Caps are recommended for wet grinding with buffers or solvents.
NOTE: Polyethylene Vials are relatively pliable compared to Polycarbonate Vials and are not as effective when used on large, hard samples (e.g., corn kernels). Polycarbonate Vials are also preferred for cryogenic grinding.
Each 4 ml Polyethylene Vial has a working volume of 4 ml and is suitable for homogenizing up to 200 mg of sample.
Each 24 Well Polyethylene Vial Set contains twenty-four (24) 4 ml Polyethylene Vials with Lined Polypropylene Screw Caps arranged in the standard SBS (Society of Biomolecular Screening) 24 well format. Each vial is pre-loaded with one (1) pre-cleaned 3/8" 440C stainless steel grinding ball. The vials are packaged in a foam holder in a polyethylene storage box, similar in size to a deep well titer plate; once the lid to the storage box is removed, it may be used to hold the vials during processing.
To use, simply remove the lid from the storage box, remove the vial caps, add sample and buffer (if desired) to the vials, replace the caps, and place the entire storage box onto the homogenizer platform for ambient processing.
Sold in cases of ten vial sets (equal to 240 pre-loaded vials). Replacement vials may be purchased separately.
For more specific information regarding sample processing, please consult the Selection of Grinding Vials for Sample Processing and Bead Beating: A Primer.
Not sure where to start? Check out our application table.
4 ml Polyethylene Vials with Lined Polypropylene Screw Caps
3/8” Stainless Steel Grinding Balls
5/16” Stainless Steel Grinding Balls
Codina, A.; Renauer, P. A.; Wang, G.; Chow, R. D.; Park, J. J.; Ye, H.; Zhang, K.; Dong, M. B.; Gassaway, B.; Ye, L.; et al. Convergent Identification and Interrogation of Tumor-Intrinsic Factors That Modulate Cancer Immunity In Vivo. Cell Systems 2019, 8 (2), 136-151.e7. https://doi.org/10.1016/j.cels.2019.01.004.
Wang, G.; Chow, R. D.; Ye, L.; Guzman, C. D.; Dai, X.; Dong, M. B.; Zhang, F.; Sharp, P. A.; Platt, R. J.; Chen, S. Mapping a Functional Cancer Genome Atlas of Tumor Suppressors in Mouse Liver Using AAV-CRISPR–Mediated Direct in Vivo Screening. Science Advances 2018, 4 (2), eaao5508. https://doi.org/10.1126/sciadv.aao5508.
Wang, G.; Chow, R. D.; Ye, L.; Guzman, C. D.; Dai, X.; Dong, M. B.; Zhang, F.; Sharp, P. A.; Platt, R. J.; Chen, S. Pooled AAV-CRISPR Screen with Targeted Amplicon Sequencing. bioRxiv 2017, 153643. https://doi.org/10.1101/153643.
Chow, R. D.; Guzman, C. D.; Wang, G.; Schmidt, F.; Youngblood, M. W.; Ye, L.; Errami, Y.; Dong, M. B.; Martinez, M. A.; Zhang, S.; et al. AAV-Mediated Direct in Vivo CRISPR Screen Identifies Functional Suppressors in Glioblastoma. PMC 2017.
Chen, S.; Sanjana, N. E.; Zheng, K.; Shalem, O.; Lee, K.; Shi, X.; Scott, D. A.; Song, J.; Pan, J. Q.; Weissleder, R.; et al. Genome-Wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis. Cell 2015, 160 (6), 1246–1260. https://doi.org/10.1016/j.cell.2015.02.038.