HT 24™ Bead Beating Homogenizer

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$9,461.00

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The HT 24™ is a tabletop bead beating homogenizer that processes up to 24 microfuge tube samples at a time. The 3D motion and speed allow for thorough processing of samples, requiring an average runtime of 35 seconds. The HT 24™ bead beating homogenizer is effective for all sample types, and can be used to grind rat brain tissues for Enzyme-Linked ImmunoSorbent Assay (ELISA) and co-immunoprecipitation analysis in order to advance research in neurogenerative diseases like Alzheimer's and Parkinson's.

The digital readout of the HT 24™ bead beating homogenizer allows for accurate timing and RPM adjustments. A maximum of 50 programs can be saved for repeated sample processing, including pulse processing, to avoid temperature spikes in the sample.

The HT 24™ bead beating homogenizer accommodates 0.5 ml to 2.0 ml skirted and unskirted (i.e., conical) microfuge tubes. The homogenizer can be programmed to cycle a maximum of 10 times with up to 120-second pauses between cycles. The HT 24™ is available in 120V & 230V. Please specify if you want a Euro or UK plug when ordering the 230V.

Unsure of which pre-filled tubes to use with your samples? See our pre-filled tube comparison page.

Not sure where to start? Check out our application table for a list of samples and suggested homogenization methods.

Citations

Chutna, O., Gonçalves, S., Villar-Piqué, A., Guerreiro, P., Marijanovic, Z., Mendes, T., Ramalho, J., Emmanouilidou, E., Ventura, S., & Klucken, J. (2014). The small GTPase Rab11 co-localizes with α-synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity. Human Molecular Genetics, 23(25), 6732-6745. https://doi.org/10.1093/hmg/ddu391.(Rab11 regulates alpha-synuclein (aSyn) secretion, reduces its aggregation and toxicity, and is involved in the progression of aSyn pathology in neurodegenerative diseases like Parkinson's)

Ciltas, A. C., Karabulut, S., Sahin, B., Filiz, A. K., Yulak, F., Ozkaraca, M., Karatas, O., & Cetin, A. (2023). FGF-18 alleviates memory impairments and neuropathological changes in a rat model of Alzheimer’s disease. Neuropeptides, 101, 102367. https://doi.org/10.1016/j.npep.2023.102367 (Fibroblast growth factor 18 (FGF18) may help treat Alzheimer's disease by improving cognitive function, reducing amyloid beta accumulation, and alleviating neuronal damage in a rat model)

Ekici, M., Güngör, H., & Mert, D. (2023). Kaempferol and Isorhamnetin alleviate Lipopolysaccharide-Induced Anxiety and Depression-Like Behavioral in Balb/C Mice. Journal of the Hellenic Veterinary Medical Society, 74(2), 5749–5760. https://doi.org/10.12681/jhvms.30232 (Kaempferol and Isorhamnetin may help treat anxiety and depression by reducing oxidative stress and inflammation, and reversing decreases in brain-derived neurotrophic factor (BDNF) levels in mice)

Additional Info

BM-D2400_HT_24_120V_User_Guide.pdf (1.9 MB)

The HT 24™

is a tabletop bead beater that processes up to 24 microfuge tube samples at a time. The 3D motion and speed allows for thorough processing of samples, requiring an average runtime of 35 seconds.

The digital readout allows for accurate timing and RPM adjustments. A maximum of 50 programs can be saved for repeated sample processing, including pulse processing, to avoid temperature spikes in the sample.

The HT 24™ accommodates 0.5 ml to 2.0 ml skirted and unskirted (i.e., conical) microfuge tubes. A pause from 1 second to 2 minutes can be programmed into the sample processing time with up to 10 cycles. The HT 24™ is available in 120V & 230V. Please specify if you would like a Euro plug or UK plug when ordering the 230V.

Unsure of which pre-filled tubes to use with your samples? See our pre-filled tube comparison page.

Not sure where to start? Check out our application table for a list of samples and a suggested homogenization method.

Citations

Chutna, O.; Gonçalves, S.; Villar-Piqué, A.; Guerreiro, P.; Marijanovic, Z.; Mendes, T.; Ramalho, J.; Emmanouilidou, E.; Ventura, S.; Klucken, J.; et al. The Small GTPase Rab11 Co-Localizes with α-Synuclein in Intracellular Inclusions and Modulates Its Aggregation, Secretion and Toxicity. Hum Mol Genet 2014, 23 (25), 6732–6745. https://doi.org/10.1093/hmg/ddu391.