HOMOGENIZERS
Mechanical homogenization procedures generate lysates with characteristics different than those produced by chemical lysis. A variety of devices are used to homogenize samples. In all cases, the tube, vial or plate is shaken so that grinding media can impact and disrupt the sample. Regardless of the mechanical approach, whether it is to beat, grind, shear, or explode cells, they are tools that can be applied in many different ways to sample preparation. Read More
NUCLEIC ACIDS EXTRACTION RESEARCH KITS
Synergy™ incorporates the bead beating step of homogenization into the purification scheme using a proprietary chemistry that binds contaminants to the Synergy™ grinding matrix. Our Synergy™ extraction platform features proprietary technology to isolate high quality Nucleic Acids in a timely and cost-efficient manner without the use of hazardous chloroform. Read More
GRINDING BEADS & PRE-FILLED DISRUPTION TUBES/PLATES
Grinding beads are either zirconium silicate or silica (soda lime) and can be purchased in a variety of sizes and grades, in bulk bottles or dispensed into disruption tubes. There are three grades of grinding beads are produced by OPS Diagnostics. Read More
GRINDING BALLS & SATELLITES
Larger and more resilient samples can be homogenized with the use of grinding balls or satellites. In contrast to grinding beads, which are pools of irregularly shaped beads in a given size range, grinding balls and satellites are spherical and precision ground to a specific diameter. They can be made of stainless steel, tungsten carbide, or zirconium oxide. The harder material does not break during extended homogenization protocols, making it preferrable to the softer silica grinding beads, for harder samples. Read More
GRINDING VIALS, PLATES, & TUBES
Bead beating can be performed in a variety of vessels, including tubes, vials and plates. In order to thoroughly homogenize a sample, the nature of the sample and its mass (size) must be matched with both a suitable vessel (vial, plate, tube) and the appropriate grinding media. OPS Diagnostics' grinding vials are self-standing and have a re-enforced flat bottom to prevent cracking of the base during homogenization. Read More
PRESERVATION & STORAGE
Freeze drying (lyophilization) is an established method for long-term storage, of biomolecules. The general process is used to preserve bacteria, fungi, yeasts, proteins, nucleic acids, and any other molecules which may degrade in the presence of water. Read More
Freezing, either cryogenically (below -130°C) in liquid nitrogen or at higher temperatures in standard laboratory freezers, is the most popular form of preservation. Many occasions require the handling of cryogenically preserved cells and biological samples. Read More